Daily Scientific Program

Day 1, Oct. 5 (Fri)

 

Place: Halla Hall, 3F, ICC Jeju

Pre-congress workshop 1

Practical Implementation of Ketogenic Therapy I 13:00-15:10

Chair(s)Eric Kossoff, Christina Bergqvist
[13:00-13:40]  Introduction to the KDEric Kossoff (USA)
[13:40-14:20]  Overview of the mechanisms of the KDJong Rho (Canada)
[14:20-15:00]  Indication of the KD (epilepsy, autism, brain cancer and other neurologic disorders) Ingrid Scheffer (Australia)

Break

15:10-15:30

Place: Halla Hall, 3F, ICC Jeju

Pre-congress workshop 2

Practical Implementation of Ketogenic Therapy II 15:30-17:20

Chair(s)Elizabeth Thiele, Beth Zupec-Kania
[15:30-16:00]  Diverse ketogenic therapies (Classic, Atkins, Modified Atkins, and Low glycemic index treatment)Elizabeth Thiele (USA)
[16:00-16:40]  Practical dietary procedure for ketogenic therapies Beth Zupec-Kania Meredith Hornbuckle Lisa Vanatta (USA)
[16:40-17:10]  Management and prevention for complications of the ketogenic therapiesJoo Hee Seo (USA)
Place: Halla Hall, 3F, ICC Jeju

Pre-congress workshop 2

Practical Implementation of Ketogenic Therapy II 17:10-17:20

Chair(s)Elizabeth Thiele, Beth Zupec-Kania
Place: Oceanview, 3F, ICC Jeju

Welcome Reception

18:30-20:30

Day 2, Oct. 6 (Sat)

 

Place: Halla Hall, 3F, ICC Jeju

Welcome

08:00-08:15

[08:00-08:15]  WelcomeHeung Dong Kim (Korea)
Jong Rho (Canada)
Jim Abrahams (USA)
Place: Halla Hall, 3F, ICC Jeju

Special lecture 1

Revisiting the KD and related therapies in the modern era08:15-08:45

Chair(s)Ingrid Scheffer
[08:15-08:45]  Revisiting the KD and related therapies in the modern eraHeung Dong Kim (Korea)
Place: Halla Hall, 3F, ICC Jeju

Main session 1

Dietary therapy for epilepsy: Recent update08:45-10:25

Chair(s)Heung Dong Kim, Ingrid Scheffer
[08:45-09:10]  KD therapy and epilepsy geneticsIngrid Scheffer (Australia)
[09:10-09:35]  Impaired signaling pathways in epilepsies and other diseasesAmy Brooks-Kayal (USA )
[09:35-09:55]  Revised recommendation of KD from international consensusEric Kossoff (USA)
[09:55-10:15]  Expanding KD therapy from infancy to adultHelen Cross (UK)

Break

10:25-10:40

Place: Halla Hall, 3F, ICC Jeju

Parallel Session 1

KD therapy in epilepsy syndromes 10:40-12:00

Chair(s)Tae Sung Ko, Hirokazu Oguni
[10:40-11:00]  Early onset epileptic encephalopathy (EIEE, WS, etc)Douglas Nordli (USA)
[11:00-11:20]  Dravet syndromeChristina Bergqvist (USA)
[11:20-11:40]  Myoclonic-atonic epilepsyHirokazu Oguni (Japan)
[11:40-12:00]  Structural epilepsyDa Eun Jung (Korea)
Place: Samda Hall, 3F, ICC Jeju

Parallel Session 2

Methods for improving KD compliance10:40-12:00

Chair(s)Sang Ook Nam, Janak Nathan
[10:40-11:00]  Premade keto meals, snacks, supplements, and formulasPavel Klein (USA)
[11:00-11:20]  Strategies for providing patient access to diet clinics and dietitian supportJanak Nathan (India)
[11:20-11:40]  Psychological strategies to improve compliance Se Hee Kim (Korea)
[11:40-12:00]  Modified diets for adolescents and adults with intractable epilepsy Antoaneta Balabanov (USA)

Lunch

12:00-13:30

Place: Halla Hall, 3F, ICC Jeju

Main session 2

Delving into the details of ketogenic nutrition 13:30-15:20

Chair(s)Beth Zupec-Kania, Songmi Lee
[13:30-13:50]  An overview of micronutrients and their potential for insufficiency in KD therapiesHeidi Pfeifer (USA)
[13:50-14:10]  Supplementing with nutrients that may benefit KD therapy; vitamin D, electrolytes, carnitine and othersDenise Potter (USA)
[14:10-14:30]  Fats and oils contribute important nutrients to ketogenic therapiesKelly Roehl (USA)
[14:30-14:50]  Constipation, renal stones and acute illnesses on KDEunjoo Lee (Korea)
[14:50-15:10]  Evidence of KD in adultMackenzie Cervenka (USA)
Place: Halla Hall, 3F, ICC Jeju

Parallel Session 3

Individualized diet therapy - Choosing the right KD therapy for the right patient 15:40-17:20

Chair(s)Elizabeth Thiele, Mackenzie Cervenka
[15:40-16:05]  Use of the KD therapy in neonatesLindsey Thompson (USA)
[16:05-16:30]  LGIT for Angelman syndromeElizabeth Thiele (USA)
[16:30-16:55]  KD for Rett syndromePi-Lien Hung (Taiwan)
[16:55-17:20]  KD therapy for mitochondrial disorders Young Mock Lee (Korea)
Place: Samda Hall, 3F, ICC Jeju

Parallel Session 4

Basic research for testing KD therapies15:40-17:20

Chair(s)Robin Williams, Byung Ho Cha
[15:40-16:00]  Understanding KD with rodent epilepsy modelsDo-Young Kim (USA)
[16:00-16:20]  Yeast models move understanding of ketogenic mechanismsRobin Williams (UK)
[16:20-16:40]  Cellular insights into KD therapiesSimon Heales (UK)
[16:40-17:00]  Fatty acid for glioblastoma bioenergeticsSeok-Gu Kang (Korea)
[17:00-17:20]  Optogenetic approachesEunji Cheong (Korea)

Day 3, Oct. 7 (Sun)

 

Place: Halla Hall, 3F, ICC Jeju

Special lecture 2

Basic mechanism of KD action08:00-08:30

Chair(s)Douglas Nordlli
[08:00-08:30]  Basic mechanism of KD actionJong Rho (Canada)
Place: Halla Hall, 3F, ICC Jeju

Main session 3

Recent and future of clinical trials on KD in the epilepsy field08:30-10:10

Chair(s)Stéphane Auvin, Huei-Shyong Wang
[08:30-09:00]  Clinical trial designs for rare diseases - new ways of thinkingSabine Scholl-Bürgi (Austria)
[09:00-09:30]  Clinical trial design for KD therapies - promoting international collaborationKi Joong Kim (Korea)
[09:30-10:00]  Designing a KD study with gut microbiotaSe Heon Kim (Korea)

Break

10:10-10:30

Place: Halla Hall, 3F, ICC Jeju

Parallel Session 5

Brain-Gut inter-relationships10:30-12:10

Chair(s)Jong Rho, Derrick Chan Wei Shih
[10:30-10:55]  What is the impact of the microbiome on brain cellular metabolism?Jong Rho (Canada)
[10:55-11:20]  An overview of human and model organism microbiomesIn-Geol Choi (Korea)
[11:20-11:45]  Potential role of microbiota in immunity and epilepsyDerrick Chan Wei Shih (Singapore)
[11:45-12:10]  Effects of the KD in experimental models of neurological diseaseJane Shearer (Canada)
Place: Samda Hall, 3F, ICC Jeju

Parallel Session 6

KD therapies and sleep10:30-12:10

Chair(s)Kristina Simeone, Kyu Young Chae
[10:30-10:55]  KD treatment and sleep in epilepsyMing-Yu Chang (Taiwan)
[10:55-11:20]  Mediterranean diet and sleepTBD (TBD)
[11:20-11:45]  Intermittent fasting and sleepHyang Woon Lee (Korea)
[11:45-12:10]  Temporal effects of the KD on cardiac-respiratory pathology in a model of SUDEP Kristina Simeone (USA)

Lunch

12:10-13:30

Place: Halla Hall, 3F, ICC Jeju

Main session 4

KD for status epilepticus13:30-15:20

Chair(s)Rima Nabbout, Jeehun Lee
[13:30-13:55]  KD therapy for super-refractory status epilepticusMackenzie Cervenka (USA)
[13:55-14:20]  Pearls and pitfalls for emergency KD use in pediatricsRima Nabbout (France)
[14:20-14:45]  Parenteral vs. enteral ketosis induction in super-refractory status epilepticusSirinuch Chomtho (Thailand)
[14:45-15:10]  Favorable factors for KD response in super-refractory status epilepticusJeehun Lee (Korea)

Break

15:20-15:40

Place: Halla Hall, 3F, ICC Jeju

Parallel session 7

Glut1-deficiency and KD: past, presence and future15:40-17:20

Chair(s)Jong Hee Chae, Joerg Klepper
[15:40-16:00]  Clinical spectrum and genetic mechanism of GLUT1-DSYasushi Itoh (Japan)
[16:00-16:20]  Have we done wrong? Long term follow-up of cardiovascular risk factors in Glut1 Deficiency treated with KD therapiesNicole Heussinger (Germany)
[16:20-16:40]  Use and potential of the modified Atkins Diet in Glut1DJeong A Kim (Korea)
[16:40-17:00]  The future therapy of Glut1D; triheptanoin and ketoesters Hoon-Chul Kang (Korea)
[17:00-17:20]  Glut1D and KD : where will we be in 2025?Joerg Klepper (Germany)
Place: Samda Hall, 3F, ICC Jeju

Parallel session 8

Basic research for KD therapies15:40-17:20

Chair(s)Sookyong Koh, Ji Eun Choi
[15:40-16:05]  Regulation of systemic inflammation by metabolic substratesEmily Goldberg (USA)
[16:05-16:30]  Anti-inflammatory targets for epilepsy: drugs vs. dietsSookyong Koh (USA)
[16:30-16:55]  Role of KD therapy in autoimmune encephalitis I-Jun Chou (Taiwan)
[16:55-17:20]  Clinical studies and anti-inflammatory mechanisms of diet treatments Stéphane Auvin (France)
Place: Lobby, 3F, ICC Jeju

Poster rounding and discussion

18:00-20:00

Day 4, Oct. 8 (Mon)

 

Place: Halla Hall, 3F, ICC Jeju

Special lecture 3

Disease-modifying, anti-epileptogenic, and neuroprotective effects of the KD: clinical implications08:00-08:30

Chair(s)Manisha Patel
[08:00-08:30]  Disease-modifying, anti-epileptogenic, and neuroprotective effects of the KD: clinical implicationsMichael Wong (USA)
Place: Halla Hall, 3F, ICC Jeju

Main session 5

Identifying signaling pathways targeted by KD : first steps towards precision medicine 08:30-10:10

Chair(s)Manisha Patel, Michael Wong
[08:30-09:00]  Metabolomic identification of altered signaling pathways by KDManisha Patel (USA)
[09:00-09:30]  Ketone bodies as signaling molecules or PPAR-mediated signaling by the KDTim Simeone (Canada)
[09:30-10:00]  Metabolic dysfunction underlying autism spectrum disorder and potential treatment approachesSusan Masino (USA)

Break

10:10-10:30

Place: Halla Hall, 3F, ICC Jeju

Parallel session 9

Expanding the use of the KD therapy 10:30-12:10

Chair(s)Sookyong Koh, Sang Ook Nam
[10:30-10:50]  Modified diets for better compliance, including non-traditional useBobbie Henry-Barron (USA)
[10:50-11:10]  KD therapy for autism spectrum disorder Ning Cheng (Canada)
[11:10-11:30]  KD therapy for cognitive impairment, mental retardation and Alzheimer's diseaseDanna Zhu (China)
[11:30-11:50]  KD therapy after resected pancreatic cancer Chang Moo Kang (Korea)
[11:50-12:10]  KD therapy for brainstem tumorsKuang-Lin Lin (Taiwan)
Place: Samda Hall, 3F, ICC Jeju

Parallel session 10

Expansion to Asia: bringing ketogenic therapies to our region I10:30-12:10

Chair(s)Teik Beng Khoo, Yuwu Jiang
[10:30-10:50]  Multi-center control trial for KD treating West syndrome in Chinese patients Yuwu Jiang (China)
[10:50-11:10]  China: helping build centers for excellence Liao Jianxiang (China)
[11:10-11:30]  Indian perspectiveJanak Nathan Suvasini Sharma (India)
[11:30-11:50]  Experience of KD: Malaysian perspectiveTeik Beng Khoo (Malyasia)
[11:50-12:10]  Experience with the KD in the PhilippinesBenilda Sanchez-Gan (Philippines)

Lunch

12:10-13:40

Place: Halla Hall, 3F, ICC Jeju

Parallel session 11

Diverse targets with mTOR pathway disorders for diet therapies13:30-15:00

Chair(s)Michael Wong, Hoon-Chul Kang
[13:30-14:00]  The mTOR pathway as a target for dietary therapy in epilepsy and related disordersMichael Wong (USA)
[14:00-14:30]  GATOR complex genes as a potential therapeutic targets of diet therapyStéphanie Baulac (France)
[14:30-15:00]  Diet therapy for the management of epilepsy associated to toropathiesHoon-Chul Kang (Korea)
Place: Samda Hall, 3F, ICC Jeju

Parallel session 12

Expansion to Asia: bringing ketogenic therapies to our region II 13:30-14:45

Chair(s)Shahnaz Ibrahim, Soon Hak Kwon
[13:30-13:45]  Experience of the KD: the Parkistani perspectiveShahnaz Ibrahim (Pakistan)
[13:45-14:00]  Experience of the KD from Saudi ArabiaAdel Mahmoud (Saudi Arabia)
[14:00-14:15]  Experience from South AfricaKath Megaw (South Africa)
[14:15-14:30]  KD Experience in Thailand Krisnachai Chomtho (Thailand)
[14:30-14:45]  Experience of the KD: an Iranian perspectiveParvaneh Karimzadeh (Iran)

Break

15:00-15:20

Place: Halla Hall, 3F, ICC Jeju

Hand over session

15:20-15:50

Chair(s)Jong Rho, Helen Cross
[15:20-15:50]  Hand over sessionHeung Dong Kim (Korea)
Helen Cross
Place: Halla Hall, 3F, ICC Jeju

Regional committee meeting

16:30-17:30

Place: Aldre Hall, Seaes Hotel Jeju

Gala Dinner

19:00-21:00

Day 5, Oct. 9 (Tue)

 

Simultaneous interpretation between Korean and English will be provided for Family support group session &
     The keto workshop for dietitians
Place: Samda Hall, 3F, ICC Jeju

Family support group

Preparing a family for the KD therapy09:00-12:00

Chair(s)Sookyong Koh, Dawn Marie Martenz
[09:00-09:30]  Caring for a child with epilepsySookyong Koh (USA)
[09:30-10:00]  Bringing parents to the tableNatasha Schoeler (UK)
[10:00-10:30]  Nursing know-how in diet complianceBrialie Forster (Australia)
[10:30-11:00]  How parent support groups may helpSue Wood (UK)
[11:00-11:30]  Support from Charlie FoundationDawn Marie Martenz (USA)
[11:30-12:00]  Psychological support for family with intractable epilepsySoyong Eom (Korea)
Place: Halla Hall, 3F, ICC Jeju

The keto workshop for dietitians

KD meal planning strategies 09:00-12:00

Chair(s)Beth Zupec-Kania, Songmi Lee
[09:00-09:30]  Initiation of the KDElizabeth Neal (UK)
[09:30-10:00]  Monitoring and supplementation of the KDHeidi Pfeifer (USA)
[10:00-10:30]  Sharing KD recipes and cooking demonstrations Eunjeung Choi (Korea)
[10:30-11:00]  KD therapy for malignancy Songmi Lee (Korea)
[11:00-11:30]  Mobile apps for KD meal planningEunjoo Lee (Korea)
[11:30-12:00]  Application of cooking oils for the KD recipeHsiu-Fen Lee (Taiwan)